BDBM14190 7-cyclohexyl-N-[4-(morpholin-4-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine::pyrrolopyrimidine 13

SMILES C1CCC(CC1)n1ccc2cnc(Nc3ccc(cc3)N3CCOCC3)nc12

InChI Key InChIKey=XQVYLFQJGUZFRC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14190   

TargetAurora kinase A(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM14190(7-cyclohexyl-N-[4-(morpholin-4-yl)phenyl]-7H-pyrro...)
Affinity DataIC50:  49nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the phosphorylation of serine 10 of histone-H3 by purified recombinant murine Aurora-A enzyme....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed